Neglected Tropical Diseases

Rapidly progressive gangrenous infection destroying facial tissue in malnourished children. 90% mortality without treatment. Survivors face severe disfigurement.

Mycobacterial infection causing painless skin nodules that progress to large destructive ulcers. Third most common mycobacterial disease after TB and leprosy.

Parasitic disease transmitted by sandflies causing fever, weight loss, spleen/liver enlargement. Fatal if untreated. Affects the poorest populations.

Parasitic disease transmitted by tsetse fly. Fatal without treatment. Causes sleep disturbance, confusion, and progressive neurological decline.

Parasitic infection causing heart failure and digestive complications. Endemic in Latin America. Existing treatments are toxic and poorly effective in chronic phase.

Parasitic worm disease causing elephantiasis — extreme swelling of limbs and genitals. 120 million infected, 40 million disfigured.

Parasitic worm infection affecting 240 million people. Causes chronic organ damage to liver, intestines, lungs, and bladder. Children are most affected.

Parasitic worm infection causing severe itching, skin changes, and blindness. Second most common infectious cause of blindness.

Chronic bacterial infection causing skin lesions, nerve damage, and progressive disability. Curable with multi-drug therapy but stigma prevents treatment.

Mosquito-borne viral infection causing fever, severe joint pain, and potentially fatal hemorrhagic fever. 390 million infections per year.